Asymmetric Synthesis

Introduction to the various methodologies for the control of the absolute stereochemistry of the desired product in organic syntheses. Topics include principles of asymmetric synthesis and asymmetric catalysis, and application of chiral synthons in total synthesis.

Objectives

Methods for the synthesis of optically active compounds will be discussed, including the principles behind asymmetric reactions. Examples of asymmetric syntheses will be taken from the recent literature.

Learning Outcomes

Students will understand the importance of asymmetric synthesis and will be able to propose syntheses of molecules of reasonable complexity with control of the stereochemistry.