Asymmetric Synthesis

AY2015/2016 Semester 1

Introduction to the various methodologies for the control of the absolute stereochemistry of the desired product in organic syntheses. Topics include principles of asymmetric synthesis and asymmetric catalysis, and application of chiral synthons in total synthesis. Objectives Methods for the synthesis of optically active compounds will be discussed, including the principles behind asymmetric reactions. Examples of asymmetric syntheses will be taken from the recent literature. Learning Outcomes Students will understand the importance of asymmetric synthesis and will be able to propose syntheses of molecules of reasonable complexity with control of the stereochemistry.