Molecular Cell Biology I

AY2018/2019 Semester 2

This course will introduce the concepts of basic molecular and cell biology with emphasis on eukaryotic cells and the use of recombinant DNA methodologies to address molecular mechanisms. The course begins by looking at DNA as the carrier of genetic information and how the genetic code is used to produce proteins which carry out most of the reactions in the cell. You will be introduced to restriction enzymes and ligase ? the cornerstones of recombinant methodology. We will also explore how the cell is organized into compartments, how proteins synthesized in the cytoplasm are targeted to the various compartments, how the cell maintains its shape and size through the cytoskeleton, how cell moves and how the cell divides to produce daughter cells. Key experiments and researchers? contributions will be highlighted to inspire students. Tutorials will be used to clarify doubts and strengthen understanding.